Huh.
Well, I'd agree that Sequential Art wouldn't be suitable to classical fighting games.
However, there are plenty of other avenues - Like a different kind of crossover.
Maybe something where, instead of directly fighting enemies, you have to find more "creative" ways to defeat them. I dunno - I'm kinda stupid, so probably not.
You could also include a Scarlet and/or Think Tank mini-game, where you have to assemble a device in a short time frame. Alone, the devices are little more than novelty trophies. Yet in the "Secret Levels" of the building mini-game, you can put earlier devices together to try and accomplish a certain build.
...I dunno. I'm kind of in a less than sensible state. And I'm kind of-possibly bipolar. And I'm kind of stupid. And I kind of joined yesterday. And I'm kind of rambling.
So...I don't think that a Sequential Art video game is impossible, per se.
It would just take a lot of out-of-the-box tinkering to work.
And it would prolly work best with an original JollyJack plot.
If that would even be conceivably possible.
...Huh.